Cervical Fusion: Stem Cells

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Cervical Fusion: Stem Cells

  • Spinal Cord Injury (SCI):
    • Recovery limited
    • Poor axonal & cellular regeneration
    • Failure to replace damaged myelin
  • Stem Cells:
    • Transdifferentiation?
  • Vaquero, et. al. Histology & Histopathology (2009)
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Cervical Fusion: Stem Cells

  • Intralesional stem cell injections:
    • Rat models
    • Clinical & pathological studies promising
    • Ability to form new nervous tissue
    • Local vs. Systemic treatment
  • Vaquero, et. al. Histology & Histopathology (2009)
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Francois, et al

Cervical Fusion: Stem Cells

  • 6/10 treatment group regained ability to walk
  • 2/13 control group regained ability to walk
  • No complications in CSF injected dogs
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AJVR 2011

Stem Cells: Current Study Francois et al.

  • Ongoing safety study
  • Harvested stem cells  myeloscopic
  • NeedleView Arthroscope
A picture of the needle view endoscope suite.
A diagram of the inside of an egg.

Stem Cells: Current Study Francois et al.

  • Myeloscopy
    • Through epidural space, dura & arachnoid mater
    • Enter anterior subarachnoid space
  • Separate needle through disk
  • Injection into spinal cord under the pia mater
  • 30 Day post-mortem and histopathology results available soon
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Stem Cells: 1st Clinical Case

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Stem Cells: 1st Clinical Case 16 months post-operative

Stem Cells: 2nd Clinical Case

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A x-ray of the lower arm and wrist.

Stem Cells: 2nd Clinical Case C3/C4 Placement

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A black and white photo of scissors on a table

Stem Cells: 2nd Clinical Case

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A black and white photo of scissors on the ground.

Stem Cells: 2nd Clinical Case 9 Months post-operative