Cervical Fusion: Stem Cells
Cervical Fusion: Stem Cells
- Spinal Cord Injury (SCI):
- Recovery limited
- Poor axonal & cellular regeneration
- Failure to replace damaged myelin
- Stem Cells:
- Transdifferentiation?
- Vaquero, et. al. Histology & Histopathology (2009)
Cervical Fusion: Stem Cells
- Intralesional stem cell injections:
- Rat models
- Clinical & pathological studies promising
- Ability to form new nervous tissue
- Local vs. Systemic treatment
- Vaquero, et. al. Histology & Histopathology (2009)
Francois, et al
Cervical Fusion: Stem Cells
- 6/10 treatment group regained ability to walk
- 2/13 control group regained ability to walk
- No complications in CSF injected dogs
AJVR 2011
Stem Cells: Current Study Francois et al.
- Ongoing safety study
- Harvested stem cells myeloscopic
- NeedleView Arthroscope
Stem Cells: Current Study Francois et al.
- Myeloscopy
- Through epidural space, dura & arachnoid mater
- Enter anterior subarachnoid space
- Separate needle through disk
- Injection into spinal cord under the pia mater
- 30 Day post-mortem and histopathology results available soon
Stem Cells: 1st Clinical Case
Stem Cells: 1st Clinical Case 16 months post-operative
Stem Cells: 2nd Clinical Case
Stem Cells: 2nd Clinical Case C3/C4 Placement
Stem Cells: 2nd Clinical Case
